All posts by Peter Diamandis

Dr.Peter H. Diamandis is a Greek American engineer, physician, and entrepreneur best known for being the founder and chairman of the X PRIZE Foundation, the co-founder and chairman of Singularity University and the co-author of the New York Times bestseller Abundance: The Future Is Better Than You Think.

The 9 Mechanisms of Aging:?

email shared by Dr. Peter Diamandis

*This section was adapted from CB INSIGHTS: The Future Of Aging.Longevity, healthcare, and aging are intimately linked.With better healthcare, we can better treat some of the leading causes of death, impacting how long we live.By investigating how to treat diseases, we’ll inevitably better understand what causes these diseases in the first place, which directly correlates to why we age.Following are the nine hallmarks of aging. I’ll share examples of health-tech and longevity technologies addressing each of these in coming weeks.Genomic instability: As we age, the environment and normal cellular processes cause damage to our genes. Activities like flying at high altitude, for example, expose us to increased radiation or free radicals. This damage compounds over the course of life and is known to accelerate aging.Telomere attrition: Each strand of DNA in the body (known as chromosomes) is capped by telomeres. These short snippets of DNA repeated thousands of times are designed to protect the bulk of the chromosome. Telomeres shorten as our DNA replicates; if a telomere reaches a certain critical shortness, a cell will stop dividing, resulting in increased incidence of disease.Epigenetic alterations: Over time, environmental factors will change how genes are expressed, i.e., how certain sequences of DNA are read and the instruction set implemented.Loss of proteostasis: Over time, different proteins in our body will no longer fold and function as they are supposed to, resulting in diseases ranging from cancer to neurological disorders.Deregulated nutrient-sensing: Nutrient levels in the body can influence various metabolic pathways. Among the affected parts of these pathways are proteins like IGF-1, mTOR, sirtuins, and AMPK. Changing levels of these proteins’ pathways have implications on longevity.Mitochondrial dysfunction: Mitochondria (our cellular power plants) begin to decline in performance as we age. Decreased performance results in excess fatigue and other symptoms of chronic illnesses associated with aging.Cellular senescence: As cells age, they stop dividing and cannot be removed from the body. They build up and typically cause increased inflammation.Stem cell exhaustion: As we age, our supply of stem cells begins to diminish as much as 100 to 10,000-fold in different tissues and organs. In addition, stem cells undergo genetic mutations, which reduce their quality and effectiveness at renovating and repairing the body.Altered intercellular communication: The communication mechanisms that cells use are disrupted as cells age, resulting in decreased ability to transmit information between cells.ConclusionOver the past 200 years, we have seen an abundance of healthcare technologies enable a massive lifespan boom.Now, exponential technologies like artificial intelligence, 3D printing and sensors, as well as tremendous advancements in genomics, stem cell research, chemistry and many other fields, are beginning to tackle the fundamental issues of why we age. In next week’s blog, we will dive into how genome sequencing and editing, along with new classes of drugs, are augmenting our biology to further extend our healthy lives.What will you be able to achieve with an extra 30 to 50 healthy years (or more) in your lifespan? Personally, I’m excited for a near-infinite lifespan to take on Moonshots.(Note: If you like this blog, share it! | Facebook | Twitter | LinkedIn | Read on Diamandis.com | Or send your friends and family to this link to subscribe!)Join Me(1) Platinum Longevity & Immunity TripThis August 19-23, 2020 and September 16-20, 2020, I’m taking two groups of VIP entrepreneurs and investors on what I call my “Platinum Longevity & Immunity Trip” to San Francisco & San Diego.Each trip will be a 5-Star (luxury) deep dive to meet 20+ companies and 30+ scientists/physicians and entrepreneurs who are leading the charge against age-related diseases and extending the human healthspan. We will also be visiting the top labs and scientists developing the diagnostics, anti-virals, vaccines and therapeutics fighting COVID-19.Both trips are identical (with only 24 participants per trip). I will spend all 5-days with you as your private guide and provocateur. Through this personalized, action-packed program, my mission is to give you first-hand exposure to the major players, scientists, companies and treatments in the longevity and vitality arena. All your questions answered. Early access to cutting-edge treatments and products. And a behind-the scenes view of tomorrow’s longevity revolution.Both trips are nearly sold out. To learn more and lock in your seat, visit our website here or email Claire Adair (claire@diamandis.com) for more details.(2) Join FutureLoop: Over the past 2 years, I’ve built a machine-learning algorithm that scrapes the world’s news, science journals and social feeds every day to understand how exponential technologies are impacting specific topics & industries. It’s called FutureLoop.Last month, I launched FutureLoop Pandemic Special Edition,” a daily comprehensive update on the impact of exponential technologies (AI, Robotics, Drones, Cellular Medicine, CRISPR, Networks & Sensors) on the COVID-19 pandemic.If you participate, FutureLoop will update you every day on the latest breakthroughs in detection, prevention & cure of the COVID-19. This product is still in Beta, but it’s powerful, high-quality info, and it’s free.Your mindset is your most important tool during this pandemic. Making sure you are consuming the right information is critical to maintaining that mindset. FutureLoop offers “Data-Driven Optimism.”You can subscribe here. It’s free, fun + fast (20 seconds).
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AI, Quantum & Entrepreneurship in China

Peter DiamandisDr.Peter H. Diamandis is a Greek American engineer, physician, and entrepreneur best known for being the founder and chairman of the X PRIZE Foundation, the co-founder and chairman of Singularity University and the co-author of the New York Times bestseller Abundance: The Future Is Better Than You Think.

Last week, Eric Schmidt, Chairman of Alphabet, predicted that China will “rapidly overtake the U.S. in artificial intelligence… in as little as five years.”

Last month, China announced plans to open a $10 billion quantum computing research center in 2020.

Bottom line, China is aggressively investing in exponential technologies, pursuing a bold goal of becoming the global AI superpower by 2030.

Based on what I’ve observed from China’s entrepreneurial scene, I believe they have a real shot of hitting that goal.

As I described in a previous tech blog, I recently traveled to China with a group of my Abundance 360 members, where I was hosted by my friend Kai Fu Lee, the founder of Sinnovation Ventures.

On one of our first nights, Kai Fu invited us to a special dinner at DaDong Roast, which specializes in Pei King duck, where we shared an 18-course meal.

The meal was amazing, and Kai Fu’s dinner conversation provided us priceless insights on Chinese entrepreneurs.

Three topics opened my eyes. Here’s the wisdom I’d like to share with you.

  1. The Entrepreneurial Culture in China

Chinese entrepreneurship has exploded onto the scene and changed significantly over the past 10 years.

IMHO, one significant way that Chinese entrepreneurs vary from their American counterparts is in work ethic. The mantra I found in the startups I visited in Beijing and Shanghai was “9-9-6” – meaning the employees only needed to work from 9 am to 9 pm, 6 days a week.

Continue reading AI, Quantum & Entrepreneurship in China

The Future of Education – Personalized, Perfect & Free (Thanks to AI and VR)

Peter Diamandis

Dr.Peter H. Diamandis is a Greek American engineer, physician, and entrepreneur best known for being the founder and chairman of the X PRIZE Foundation, the co-founder and chairman of Singularity University and the co-author of the New York Times bestseller Abundance: The Future Is Better Than You Think.
Right now, online platforms like Khan Academy and Coursera have made a plethora of educational resources available 1) for free and 2) on demand, such that you can pick and choose what you learn and at what speed you learn it.

Khan Academy has delivered over 300 million lessons since it started in 2006, features 5,000 free instructional videos in 65 languages, and allows users to complete 4 million exercises every day – simply amazing.

Continue reading The Future of Education – Personalized, Perfect & Free (Thanks to AI and VR)

Can a company actually disrupt itself?

Peter DiamandisDr.Peter H. Diamandis is a Greek American engineer, physician, and entrepreneur best known for being the founder and chairman of the X PRIZE Foundation, the co-founder and chairman of Singularity University and the co-author of the New York Times bestseller Abundance: The Future Is Better Than You Think.

I often say that businesses must disrupt themselves (before someone else does) to survive.

The fact of the matter is: very few companies have actually successfully disrupted themselves.

Instead, most successful companies “disrupt adjacencies”: they leverage their existing assets to expand into new, high growth markets. They actually disrupt someone else!

Let’s start with a few disruption examples.

FACEBOOK Disrupts SMS MESSAGING: Facebook decided to disrupt SMS messaging with the launch of Messenger. Because Facebook is a platform, they have been able to garner 700M monthly active users globally – driving a projected 38% decline in Telco SMS revenue in North America by 2017.

TESLA Disrupts ENERGY STORAGE: Tesla, an electric car company, is disrupting energy storage with the Tesla Powerwall. They used the technology developed for their cars to branch into this new ($19 billion) market.

GOOGLE disrupts MOBILE PHONES: Google is an Internet search company, but in 2008, Google got into the phone/hardware business, shipping Android and beginning the disruption of mobile operating systems. Android currently commands an astounding 82.8% market share.

Continue reading Can a company actually disrupt itself?

a genomics (r)evolution?

Peter DiamandisDr.Peter H. Diamandis is a Greek American engineer, physician, and entrepreneur best known for being the founder and chairman of the X PRIZE Foundation, the co-founder and chairman of Singularity University and the co-author of the New York Times bestseller Abundance: The Future Is Better Than You Think.

Humanity is moving from evolution by natural selection (Darwinism) to evolution by intelligent direction.

For most of human history, our average age was only about 26 years old.

We would procreate at age 13, live just long enough to help our children raise their children, and then, on average, die at age 26 (so we were no longer taking food from the mouths of our grandchildren).

It was through technological innovation — sanitation and germ theory — that we moved life expectancy from 26 to the mid 50’s. Recently, because of modern medicine’s progress in treating heart disease and cancer, we’ve bumped up today’s global average human lifespan to 71 years.

But this is just the beginning.

Advances over the next 10 to 15 years will move life expectancy north of 100.

This blog is about advances in reading, writing, and building elements of the human body.

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Reading – Sequencing the Human Genome

Your genome is the software that runs your body.

It is composed of 3.2 billion “letters,” or base pairs, that code foreverything that makes you “you” – your hair color, your height, your personality, your propensity to disease, your lifespan, and so on.

Until recently, it’s been very difficult to rapidly and cheaply “read” these letters and even more difficult to understand what they do.

In 2001, my friend and Human Longevity Inc. co-founder Dr. J. Craig Venter sequenced the first complete human genome. It took about a year and cost $100 million.

Since then, the cost to sequence a genome has been plummeting exponentially, outpacing Moore’s Law by almost 3x (take a look at the graph below).

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(Figure: The cost of genome sequencing drops 3x faster than Moore’s Law)

Today, the cost to sequence a full human genome is about $1,000.

Continue reading a genomics (r)evolution?

Learning in Exponential Times?

Peter DiamandisDr. Peter H. Diamandis is a Greek American engineer, physician, and entrepreneur best known for being the founder and chairman of the X PRIZE Foundation, the co-founder and chairman of Singularity University and the co-author of the New York Times bestseller Abundance: The Future Is Better Than You Think

How to learn is changing, and it’s changing fast.

In the past, we used to learn by doing – we called them apprenticeships.

Then the model shifted, and we learned by going to school.

Now, it’s going back to the apprenticeship again, but this time, you are both the apprentice and the master.

This blog is about how to learn during exponential times, when information is abundant and expertise is fleeting.

Passion, Utility, Research & Focus

First, choosing what you want to learn and becoming great at it is tough.

As I wrote in my last blog, doing anything hard and doing it well takes grit.

Here are a few tips I’ve learned over the years to help choose what you want to learn:

Continue reading Learning in Exponential Times?

The Future of Transportation?

Peter DiamandisDr. Peter H. Diamandis is a Greek American engineer, physician, and entrepreneur best known for being the founder and chairman of the X PRIZE Foundation, the co-founder and chairman of Singularity University and the co-author of the New York Times bestseller Abundance: The Future Is Better Than You Think

Four revolutions in transportation are taking place this decade.

In 2011, Peter Thiel famously said, “We wanted flying cars, instead we got 140 characters…”

Guess what? The flying car is coming, and so is a heck of a lot more.

I want to explore the latest developments in:

–Autonomous Vehicles

–Telepresence Robots & Virtual Worlds

–Hyperloop

–Point-to-Point Aerial Transport

–Each of these will change where we live, work and interact.

Continue reading The Future of Transportation?

The World in 2025: 8 Predictions for the Next 10 Years

Peter DiamandisDr.Peter H. Diamandis is a Greek American engineer, physician, and entrepreneur best known for being the founder and chairman of the X PRIZE Foundation, the co-founder and chairman of Singularity University and the co-author of the New York Times bestseller Abundance: The Future Is Better Than You Think.

In 2025, in accordance with Moore’s Law, we will see an acceleration in the rate of change as we move closer to a world of true abundance.

Here are eight areas where we’ll see extraordinary transformation in the next decade:

A $1,000 Human Brain: In 2025, $1000 should buy you a computer able to calculate at 10^16 cycles per second (10,000 trillion cycles per second), the equivalent processing speed of the human brain.

A Trillion-Sensor Economy: The Internet of Everything describes the networked connections between devices, people, processes and data. By 2025, the IoE will exceed 100 billion connected devices, each with a dozen or more sensors collecting data. This will lead to a trillion-sensor economy driving a data revolution beyond our imagination. Cisco’s recent report estimates the IoE will generate $19 trillion of newly created value.

Continue reading The World in 2025: 8 Predictions for the Next 10 Years

Rising Billions – dramatic (positive) change?

Peter DiamandisDr.Peter H. Diamandis is a Greek American engineer, physician, and entrepreneur best known for being the founder and chairman of the X PRIZE Foundation, the co-founder and chairman of Singularity University and the co-author of the New York Times bestseller Abundance: The Future Is Better Than You Think.

The most dramatic (positive) change in our global economy is about to occur between 2016 and 2020.

Three to five billion new consumers, who have never purchased anything, never uploaded anything, and never invented and sold anything, are about to come online and provide a mega-surge to the global economy.

While most of these individuals are in Africa, India, China and the developing world, and their income is low, when aggregated, this represents tens of trillions of new dollars flowing into the global economy… and no one is talking about it.

I call this group the “Rising Billions.”

What are you going to sell to them?

How are they going to compete with you?

The Rising Billions are not coming online like we did 20 years ago with a 9600 modem on AOL. They’re coming online with a 1 Mbps connection and access to the world’s information on Google, cloud 3D printing, Amazon Web Services, artificial intelligence with Watson, crowdfunding, crowdsourcing, and more.

This is about how the Rising Billions are connecting and the implications to you, your industry and our global economy.

The Technology Connecting the World

While the Internet has been extraordinary, it has only until recently connected the wealthiest.

In 2010, 1.8 billion people were connected.

Today, five years later, about 2.8 billion are connected…

ImageProxy

Graph – Internet Users in the World

Continue reading Rising Billions – dramatic (positive) change?

A clash between linear and exponential systems is coming.

Peter DiamandisDr.Peter H. Diamandis is a Greek American engineer, physician, and entrepreneur best known for being the founder and chairman of the X PRIZE Foundation, the co-founder and chairman of Singularity University and the co-author of the New York Times bestseller Abundance: The Future Is Better Than You Think.

What’s a linear system? Think governments, politicians, regulators, large and slow-moving legacy companies, and the like…

What’s an exponential system? You. Today’s exponential entrepreneurs. Silicon Valley startups. Fast-moving innovators and disruptors that want to change the game.

We’ve seen indicators of the conflict as lawsuits are filed against Uber, Airbnb, Tesla, 23andMe and various drone companies.

But this is just beginning. It’s a revolution of sorts… And more is coming. A lot more.

Continue reading A clash between linear and exponential systems is coming.